WVCTSI Tech Core


Emerging Pathogens Core

The Emerging Pathogens Core provides services to clinical, translational, and basic investigators where robust technology-based infrastructure is essential to translate research focused on emerging pathogens to better health outcomes.  These services will include i) culturing pathogens and their variants, ii) developing cellular and small animal models that serve as tools to study human disease, iii) testing the efficacy of novel therapeutics, and iv) developing newly formulated vaccines and monitoring immunologic response.


Inhalation Facility


The WVU HSC Inhalation Facility is designed to generate artificial atmospheres of inhalable toxicants under tightly controlled conditions for pulmonary exposures in experimental animal models. These exposures replicate environmental and occupational inhalation exposures in humans. The facility performs whole-body and nose-only inhalation exposures to: nanomaterials, military burn pit emissions, gases, field collections from mountain top mining, fracking or heavy vehicular traffic areas, combustion emissions, 3-D printing emissions, and e-cigarette/vaping.  Real-time aerosol monitoring provides high resolution characterization of generated aerosols.  Animals can be chronically instrumented for telemetry and drug delivery. Pulmonary function can be measured non-invasively in conscious animals.


Molecular Medicine Laboratory

The Molecular Medicine Laboratory is designed to accelerate the development and implementation of molecular clinical assays. Automated liquid handling equipment allows users of the core to perform high throughput DNA/RNA extractions, PCR assays, and generation of libraries for Next Generation Sequencing.  There are separate research and clinical laboratories that are configured with identical equipment to enable seamless transfer of newly developed assays into the CLIA-certified testing lab.


Name Role Phone Email Location