The Genetic and Tumor Model Core Facility (GTM) at West Virginia University is a fee-for-service facility that is housed within the specific pathogen-free (SPF) barrier in the animal quarters at the WVU Health Sciences Center. Our services within the GTM are available to investigators at WVU and the National Institute of Occupational Safety and Health. The services currently include 1) embryo and germ cell cryopreservation of valuable genetic strains; 2) a breeding colony of Nod-SCID gamma (NSG) immunocompromised mice for sale to members of the WVU community. These NSG animals provide WVU investigators needed animals for cancer cell imaging studies and expansion of human tumor xenographs; and 3) the establishment and expansion of patient-derived xenografts (PDX) into immunocompromised mice and other specialized tumor model animal systems.
Petar Mathers, PhD
Director- Genetic and Tumor Model (GTM) Core
(304) 293-0271
pmathers@hsc.wvu.edu
Elena Pugacheva, PhD
Associate Director- GTM
(304) 293-5295
epugacheva@hsc.wvu.edu
PTM Hours | Location |
Transgenic Office Hours |
|
Name | Role | Phone | Location | |
---|---|---|---|---|
Peter Mathers, PhD |
Director- Transgenic; Associate Director- PTM
|
304-293-0271
|
pmathers@hsc.wvu.edu
|
310 BMRC
|
Elena Pugacheva, PhD |
Director- PTM Core
|
304-293-5295
|
epugacheva@hsc.wvu.edu
|
2832 HSC-S
|
Stuart Clayton, BS |
PTM Core Technician
|
304-293-0951
|
saclayton@hsc.wvu.edu
|
2nd Floor Erma Byrd
|
Services and Supplies |
► Supplies (6) | |||
Name | Description | Price | |
---|---|---|---|
Estrogen Pellet | Inquire | ||
Matrigel for tumor grafting | Inquire | ||
NSG Mice, 06 weeks or older | Inquire | ||
PDX tissue section, 1-2 slide | Inquire | ||
Tumor freezing medium | Inquire | ||
Tumor storage (1-10 vials per year) | Inquire | ||
► PDX Services (7) | |||
Name | Description | Price | |
Cell line, pdx authentication | Inquire | ||
Human Tissue procurement, CHTN | Inquire | ||
Human Tissue procurement, WVU | Inquire | ||
Time course analysis of Circulating tumor cells from perfiferal blood | Inquire | ||
Tumor cell isolation from xenografts | Inquire | ||
WVU Human Essential CLEAR panel | Inquire | ||
WVU Mouse Essential CLEAR panel | Inquire | ||
► Strain Preservation Services (1) | |||
Name | Description | Price | |
Resuscitaton from Frozen Embryos | Inquire |